Genesis 25:22-26

22The babies jostled each other within her, and she said, “Why is this happening to me?” So she went to inquire of the LORD .

23The LORD said to her, “Two nations are in your womb, and two peoples from within you will be separated; one people will be stronger than the other, and the older will serve the younger.” 24When the time came for her to give birth, there were twin boys in her womb. 25The first to come out was red, and his whole body was like a hairy garment; so they named him Esau. Esau may mean hairy.

26After this, his brother came out, with his hand grasping Esau’s heel; so he was named Jacob. Jacob means he grasps the heel, a Hebrew idiom for he deceives. Isaac was sixty years old when Rebekah gave birth to them.