Genesis 25:21-24

21Isaac prayed to the LORD on behalf of his wife, because she was childless. The LORD answered his prayer, and his wife Rebekah became pregnant.

22The babies jostled each other within her, and she said, “Why is this happening to me?” So she went to inquire of the LORD .

23The LORD said to her, “Two nations are in your womb, and two peoples from within you will be separated; one people will be stronger than the other, and the older will serve the younger.” 24When the time came for her to give birth, there were twin boys in her womb.